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生物通商城首頁 > 試劑 > 細胞生物學 > 活體成像試劑 > 定向熒光成像

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Targeted fluorescent imaging agents enable specific areas of interest to be detected, monitored and measured in vivo. These agents actively target and bind to specific biomarkers. Benefits include the agents’ highly specific targeting to key biologies.  Below is a partial list of our in vivo targeted fluorescent imaging agents.


  • GFR-Vivo 680 is a novel fluorescent imaging agent to detect Glomerular Filtration Rate to measure kidney function
  • HER2Sense targets the HER2/neu receptors that is over expressed in various breast cancer and non-breast cancer models
  • FolateRSense is highly specific to Folate Receptor protein, which is expressed by many growing tumors
  • OsteoSense agents target hydroxyapatite to enable in vivo detection and monitoring of skeletal changes that occur during bone growth or resorption
  • IntegriSense Imaging Agents target integrin αv β3 ,associated with tumor cell metastasis and the development of neovasculature (in angiogenesis)
  • RediJect 2-DG 750 targets tumor that exhibit elevated glucose uptake than surrounding tissues


産品名/貨号/品牌 簡介 包裝  
XenoLight RediJect Bacterial Detection Probe 750 Explorer kit (image 5 animals/kit) 5 Doses

價格:¥

貨号:133397
品牌:PERKINELMER

經銷:基因有限公司

XenoLight RediJect Bacterial Detection Probe is a Near-Infrared fluorescent agent for in vivo targeting of both Gram-positive and Gram-negative bacterial infections. This probe specifically targets the anionic phospholipids of bacterial cell membrane, and so targets Gram-negative bacteria slightly more efficiently than Gram-positive bacteria. RediJect Bacterial Detection Fluorescent Imaging Probe is extremely bright, allowing sensitive detection of deep-tissue infections caused by a range of bacteria, including Staphylococcus aureus, Streptococcus pneumoniae, Pseudomonas aeruginosa, Salmonella typhimurium and Escherichia coli.

XenoLight RediJect Bacterial Detection Probe 750 Control Dye 1UNIT

價格:¥

貨号:133399
品牌:PERKINELMER

經銷:基因有限公司

XenoLight RediJect Bacterial Detection control dye is a non-reactive dye that can be used as a negative control when using the RediJect Bacterial Detection 750 fluorescent imaging probe.

XenoLight RediJect 2-DG 750 Probe Explorer kit 1kitT

價格:¥

貨号:760561
品牌:PERKINELMER

經銷:基因有限公司

For in vivo targeting of tumors that typically exhibit elevated glucose uptake rate in comparison to surrounding tissues. To achieve maximum glucose targeting and enhanced tumor uptake, the probe has been designed to contain four 2-DG molecules per dye molecule. Explorer kit:1 sterile amber vial containing 600ul of 10nmoles/100ul probe

XenoLight RediJect 2-DG 750 Control Dye 1UNIT

價格:¥

貨号:760567
品牌:PERKINELMER

經銷:基因有限公司

RediJect 2-DG control dye is a non-reactive dye that can be used as a negative control when using the RediJect 2-DG-750 fluorescent imaging probe.

RediJect COX-2 probe, Explorer kit 5 Doses

價格:¥

貨号:133316
品牌:PERKINELMER

經銷:基因有限公司

A novel fluorescent imaging probe for pre-clinical research that specifically detects the cyclooxygenase-2 (COX-2) biomarker non-invasively in vivo as well as in ex vivo tissue analysis applications. PerkinElmer’s RediJect COX-2 fluorescent imaging probe provides the ability to non-invasively detect COX-2 in early-stage cancer cells, with a level of sensitivity and accuracy not attainable by conventional methods. The RediJect COX-2 probe is very specific, with good signal to background ratios, in targeting tumors that only over express the COX-2 biomarker. Images shown in figure 1 show specific targeting to HT-29 (COX-2 positive) tumors and not targeting to HCT-116 (COX-2 negative) tumors. The specificity is also confirmed in vitro with Nuance Multispectral imaging system.

RediJect COX-2 Fluorescent Imaging Probe (Control Dye) 1UNIT

價格:¥

貨号:133349
品牌:PERKINELMER

經銷:基因有限公司

RediJect COX-2 control dye is a non-reactive dye that can be used as a negative control when using the RediJect COX-2 probe.

GFR-Vivo 680 Fluorescent Imaging Agent/GFR-Vivo 680近紅外熒光探針 10 Dose

價格:¥

貨号:NEV30000
品牌:PERKINELMER

經銷:基因有限公司

GFR-Vivo 680 Standard 10 injection kitFluorescent Imaging Agent GFR-Vivo 680近紅外熒光探針,成分為近紅外熒光染料标記的菊粉,用來評估腎小球過濾率(GFR)。GFR是評估腎功能的金标準,用來判斷腎髒疾病的進展和藥物引起的腎毒性,可注射10隻小鼠。A near infrared (NIR) fluorescent-labeled form of inulin (GFR-Vivo 680) in a spectral region providing low background and high tissue penetration (ex/em = 670/685 nm) for in vivo applications. Glomerular filtration rate (GFR) is the gold standard in kidney function assessment and is used to determine progression of kidney disease and drug-induced kidney toxicity. One of the most accepted ways to assess GFR is by measuring the rate of disappearance of labeled inulin from the blood; as inulin is completely filtered at the kidneys’ glomeruli (but neither secreted nor reabsorbed by the tubules), this rate of disappearance is directly proportional to GFR.

RediJect Bacterial Detection Probe (Standard kit)/細菌檢測近紅外熒光探針 20 Dose

價格:¥

貨号:133398
品牌:PERKINELMER

經銷:基因有限公司

XenoLight RediJect Bacterial Detection Probe 750 Std. kit (image 20 animals/kit) 細菌監測試劑盒,于細菌膜表面帶負電荷的磷脂質結合而标記細菌(包括革蘭式陽性及陰性菌),代謝速度較慢,體内半衰期約為24小時,可注射20隻小鼠。 XenoLight RediJect Bacterial Detection Probe is a Near-Infrared fluorescent agent for in vivo targeting of both Gram-positive and Gram-negative bacterial infections. This probe specifically targets the anionic phospholipids of bacterial cell membrane, and so targets Gram-negative bacteria slightly more efficiently than Gram-positive bacteria. RediJect Bacterial Detection Fluorescent Imaging Probe is extremely bright, allowing sensitive detection of deep-tissue infections caused by a range of bacteria, including Staphylococcus aureus, Streptococcus pneumoniae, Pseudomonas aeruginosa, Salmonella typhimurium and Escherichia coli.

RediJect 2-DG Fluorescent Imaging Probe (Standard kit)/近紅外染料标記的脫氧葡萄糖醛酮探針 20 Dose

價格:¥

貨号:760562
品牌:PERKINELMER

經銷:基因有限公司

XenoLight RediJect 2-DG 750 Probe Standard kitFluorescent Imaging Agent 近紅外染料标記的脫氧葡萄糖醛酮,觀測腫瘤組織更加旺盛的葡萄糖代謝,可注射20隻小鼠。 For in vivo targeting of tumors that typically exhibit elevated glucose uptake rate in comparison to surrounding tissues. To achieve maximum glucose targeting and enhanced tumor uptake, the probe has been designed to contain four 2-DG molecules per dye molecule.
Novel ready-to-use probe to monitor glucose uptake in vivo non-invasively
Dispensed to image 20 animals
Maximum glucose targeting and enhanced tumor uptake
In vivo imaging quality, validated on IVIS imaging systems

RediJect COX-2 Fluorescent Imaging Probe (Standard kit)/環氧化物酶-2近紅外熒光探針成像試劑 20 Dose

價格:¥

貨号:133314
品牌:PERKINELMER

經銷:基因有限公司

RediJect COX-2近紅外熒光探針,檢測環氧化物酶2,可注射20隻小鼠。 XenoLight RediJect COX-2 is a a novel fluorescent imaging probe for pre-clinical research that specifically detects the cyclooxygenase-2 (COX-2) biomarker noninvasively in vivo as well as in ex vivo tissue analysis applications. PerkinElmer’s RediJect COX-2 fluorescet imaging probe provides the ability to non-invasively detect COX-2 in early-stage cancer cells, with a level of sensitivity and accuracy not attainable by conventional methods.

OsteoSense 680EX Fluorescent Imaging Agent/OsteoSense 680EX近紅外熒光探針成像試劑 10 Dose

價格:¥

貨号:NEV10020EX
品牌:PERKINELMER

經銷:基因有限公司

OsteoSense 680EX近紅外熒光探針,羟磷灰石成分,通過檢測骨骼中暴露的羟磷灰石含量而研究骨骼生長及重建。,可注射10隻小鼠。 A fluorescent in vivo bisphosphonate imaging agent. OsteoSense 680 EX images areas of micro-calcifications and bone remodeling and enables imaging of bone growth and resorption. OsteoSense 680 EX fluorescent imaging agent can be used to measure the effects of therapeutic stimulation of bone growth. This agent can also be used to characterize bone remodeling associated with animal models of arthritis. OsteoSense 680 EX enables in vivo detection, measurement and monitoring of skeletal changes in a wide range of disease states, including arthritis, osteoporosis, and cancer metastasis.

OsteoSense 750EX Fluorescent Imaging Agent/OsteoSense 750EX近紅外熒光探針成像試劑 10 Dose

價格:¥

貨号:NEV10053EX
品牌:PERKINELMER

經銷:基因有限公司

Agent OsteoSense 750EX近紅外熒光探針,羟磷灰石成分,通過檢測骨骼中暴露的羟磷灰石含量而研究骨骼生長及重建。,可注射10隻小鼠。 A targeted fluorescent in vivo bisphosphonate imaging agent. OsteoSense 750 EX images areas of microcalcifications and bone remodeling and enables imaging of bone growth and resorption. OsteoSense 750 EX fluorescent imaging agent can be used to measure the effects of therapeutic stimulation of bone growth. This agent can also be used to characterize bone remodeling associated with animal models of arthritis. OsteoSense 750 EX enables in vivo detection, measurement and monitoring of skeletal changes in a wide range of disease states, including arthritis, osteoporosis, and cancer metastasis

OsteoSense 800近紅外熒光成像試劑:OsteoSense 800 Fluorescent Imaging Agent 10次

價格:¥

貨号:NEV11105
品牌:PERKINELMER

經銷:基因有限公司

OsteoSense 800近紅外熒光探針,羟磷灰石成分,通過檢測骨骼中暴露的羟磷灰石含量而研究骨骼生長及重建。,可注射10隻小鼠。A targeted fluorescent in vivo bisphosphonate imaging agent. OsteoSense 800 images areas of microcalcifications and bone remodeling and enables imaging of bone growth and resorption. OsteoSense 800 fluorescent imaging agent at a wavelenth at 800 nm, can be used to measure the effects of therapeutic stimulation of bone growth. This agent can also be used to characterize bone remodeling associated with animal models of arthritis. OsteoSense 800 enables in vivo detection, measurement and monitoring of skeletal changes in a wide range of disease states, including arthritis, osteoporosis, and cancer metastasis.

HypoxiSense 680 Fluorescent Imaging Agent/HypoxiSense 680近紅外熒光探針成像試劑

價格:¥

貨号:NEV11070
品牌:PERKINELMER

經銷:基因有限公司

HypoxiSense 680近紅外熒光探針,檢測腫瘤細胞表面的碳酸酐酶9(CAIX),可注射10隻小鼠。HypoxiSense™ 680 fluorescent imaging agent detects the tumor cell surface expression of carbonic anhydrase 9 (CA IX) protein, which increases in hypoxic regions within many tumors, especially in cervical, colorectal, non-small cell lung tumors. Pairing HypoxiSense with optical fluorescent imaging technology allows you to image and quantitate tumor sub-regions undergoing hypoxia-related changes, non-invasively and in vivo.

FOLATERSENSE 680 Fluorescent Imaging Agent/FOLATERSENSE 680近紅外熒光探針成像試劑 10 Dose

價格:¥

貨号:NEV10040
品牌:PERKINELMER

經銷:基因有限公司

FOLATERSENSE 680 Fluorescent Imaging Agent FOLATERSENSE 680近紅外熒光探針,檢測腫瘤細胞表面的葉酸受體蛋白,可注射10隻小鼠。FolateRSense™ targeted fluorescence imaging agent is highly specific and sensitive in its detection of Folate Receptor alpha (FRA) and can be used to closely monitor and quantitate tumor growth and metabolism. Over-expression of FRA protein is associated with tumor growth, and uptake of folic acid is a necessary part of tumor metabolism.

TLectinSense 680 Fluorescent Imaging Agent/TLectinSense 680近紅外熒光探針成像試劑 10 Dose

價格:¥

貨号:NEV10060
品牌:PERKINELMER

經銷:基因有限公司

TLectinSense 680近紅外熒光探針,檢測血管内皮細胞表面的糖蛋白,進行血管新生及血管分布觀測,可注射10隻小鼠。A fluorescent in vivo endothelial cell imaging agent. TLectinSense 680 fluorescent agent is a near-infrared labeled macromolecule that targets the vasculature and enables imaging of blood vessels and angiogenesis. This agent in conjunction with PerkinElmer’s imaging instruments helps in assessing vascularity in vivo and in real time, without termination of mice, excision and processing of the tissue, thus improving the efficacy, early detection and monitoring of anti-angiogenic therapies.

BombesinRSense 680 Fluorescent Imaging Agent/BombesinRSense 680近紅外熒光探針 10 Mouse Dose

價格:¥

貨号:NEV10090
品牌:PERKINELMER

經銷:基因有限公司

BOMBESINRSENSE 680Fluorescent Imaging Agent BombesinRSense 680近紅外熒光探針,檢測腫瘤細胞表面的蛙皮素受體,可注射10隻小鼠。Specific for bombesin receptors (BBRs) expressed in many types of cancer. Bombesin-like peptides and their G-protein coupled receptors have been shown to play a role in cancer and are overexpressed in a variety of tumors, including prostate, breast, lung, CNS, gastric, colon, and renal cell carcinomas. BombesinRSense 680 comprises a 7-amino acid bombesin peptide analog, an NIR fluorophore (ex/em 665/691 nm) and a pharmacokinetic modifier to improve its plasma availability (plasma t1/2 = 30-45 min). This agent can be used to target and quantify upregulation of bombesin receptors (BBR) in vivo associated with tumor proliferation.

IntegriSense 680近紅外熒光成像試劑:IntegriSense 680 Fluorescent Imaging Agent 10次

價格:¥

貨号:NEV10645
品牌:PERKINELMER

經銷:基因有限公司

IntegriSense 680 Fluorescent Imaging Agent IntegriSense 680近紅外熒光探針,檢測膜整聯蛋白αvβ3,組織半衰期較長,可注射10隻小鼠。 For in vivo detection of avb3 using a low molecular weight peptidomimetic antagonist coupled to a red fluorochrome. IntegriSense 680, an integrin-targeted molecular imaging agent allows the non-invasive imaging of disease status and progression. Pairing of an integrin antagonist treatment with IntegriSense 680 provides a mechanistic biomarker approach for assessing target coverage. Integrins are transmembrane cell surface receptors which mediate signal transduction, cell-to-cell interaction and cell-to extracellular matrix adhesion, key processes involved in angiogenesis, tumorigenesis and metastasis. Integrins have thus been hailed as clinically-relevant biomarkers of pathological conditions such as inflammation and tumor progression. The integrin avb3 is significantly upregulated in tumor cells and activated endothelial cells during neoangiogenesis.

IntegriSense 750近紅外熒光成像試劑:IntegriSense 750 Fluorescent Imaging Agent 10次

價格:¥

貨号:NEV10873
品牌:PERKINELMER

經銷:基因有限公司

IntegriSense 750 Fluorescent Imaging Agent IntegriSense 750近紅外熒光探針,檢測膜整聯蛋白αvβ3,組織半衰期較長,可注射10隻小鼠。 A targeted fluorescent imaging agent comprising a potent, selective non-peptide small molecule integrin avb3 antagonist and a near- infrared (NIR) fluorochrome. IntegriSense 750 has a shorter half life in tissue than IntegriSense 680. IntegriSense 750 washes out of tissues in ~ 96 hours to permit more frequent reinjection of the agent in longitudinal studies. This agent has been developed to enable in vivo visualization and quantification of integrin avb3 in tumor cells as well as in neovasculature, to monitor tumor growth, tumor angiogenesis, and treatment efficacy. Absorbance and fluorescence emission spectra of IntegriSense 750 in 1x PBS.

IntegriSense 645近紅外熒光成像試劑:IntegriSense 645 Fluorescent Imaging Agent 10次

價格:¥

貨号:NEV10640
品牌:PERKINELMER

經銷:基因有限公司

IntegriSense 645近紅外熒光探針,檢測膜整聯蛋白αvβ3,組織半衰期較短(2天),可注射10隻小鼠。For in vivo detection of avb3 using a low molecular weight peptidomimetic antagonist coupled to a red fluorochrome. IntegriSense 645, an integrin-targeted molecular imaging agent allows the non-invasive imaging of disease status and progression. Pairing of an integrin antagonist treatment with IntegriSense 645 provides a mechanistic biomarker approach for assessing target coverage. Integrins are transmembrane cell surface receptors which mediate signal transduction, cell-to-cell interaction and cell-to extracellular matrix adhesion, key processes involved in angiogenesis, tumorigenesis and metastasis. Integrins have thus been hailed as clinically-relevant biomarkers of pathological conditions such as inflammation and tumor progression. The integrin avb3 is significantly upregulated in tumor cells and activated endothelial cells during neoangiogenesis.

Cat K 680 FAST近紅外熒光成像試劑:Cat K 680 FAST Fluorescent Imaging Agent 10次

價格:¥

貨号:NEV11000
品牌:PERKINELMER

經銷:基因有限公司

Cat K 680FAST近紅外熒光探針,檢測組織蛋白酶K的活性,可注射10隻小鼠(20-26g小鼠)。A Cathepsin K (Cat K) activatable fluorescent agent that is optically silent upon injection and produces fluorescent signal after cleavage by disease related Cathepsin K. Cat K is highly expressed in osteoclasts, suggesting a specialized role in bone resorption.
Cat K is found extracellularly along the bone and cartilage and intracellularly in lysozomes of osteoclasts attached to the bone. In addition to expression by osteoclasts, Cat K is also expressed by a broad range of other cell types including ovarian cells, colonic tissue, alveolar and bronchial epithelial cells, synovial fibroblasts, breast cancer cells, macrophages.

Annexin Vivo 750近紅外熒光成像試劑:Annexin Vivo 750 Fluorescent Imaging Agent 10次

價格:¥

貨号:NEV11053
品牌:PERKINELMER

經銷:基因有限公司

Annexin Vivo 750 Fluorescent Imaging Agent Annexin Vivo 750近紅外熒光探針,用來檢測細胞早期凋亡中外翻于細胞膜表面的磷酯酰絲氨酸,可注射10隻小鼠。 A targeted fluorescent imaging agent comprising a selective protein, Annexin A5 and a near-infrared (NIR) fluorochrome. This agent has been developed to enable in vivo visualization and quantification of the membrane-bound phospholipid, phosphotidylserine, exposed in the outer leaflet of the cell membrane lipid bilayer during the early stages of apoptosis. Annexin-Vivo 750 fluorescent imaging agent selectively binds phosphatidylserine exposed in the outer leaflet of the cell membrane during the early stages of apoptosis.
Each vial contains 10 mouse doses of Annexin-Vivo 750 in solution. Annexin-Vivo 750 is supplied in 1000 µL of 25 mM Hepes/NaOH, 140 mM NaCl, pH 7.4. The packaged material provides sufficient reagent for imaging approximately 10 mice (weighing ~25 grams each) when using the recommended dose of 100 µL of Annexin-Vivo 750 per mouse.

BacteriSense 645 Fluorescent Imaging Agent/BacteriSense 645近紅外熒光探針成像試劑 10 Mouse Dose

價格:¥

貨号:NEV10080
品牌:PERKINELMER

經銷:基因有限公司

BacteriSense 645 Fluorescent Imaging Agent BacteriSense 645近紅外熒光探針,與細菌膜表面帶負電荷的磷脂質結合而标記細菌(包含革蘭式陽性及陰性菌),代謝速度快(體内半衰期小于1小時),可注射10隻小鼠。BacteriSense™ 645 Targeted Fluorescent Pre-clinical Imaging Agent is a fast-clearing, targeted probe which binds to negatively charged lipids on the bacterial cell membrane, enabling the monitoring of infection progression in vivo non-invasively and in real time. Because the half-life of BacteriSense in vivo is as short as 45 minutes, image data can be acquired every day to track bacterial load during infection. This agent effectively targets infection caused by both gram-negative and gram-positive bacteria.

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